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Antigenic Specificity | Cellular Apoptosis Susceptibility |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation. |
Immunogen | KLH-conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility. |
Other Names | CSE1L, CAS, XPO2, Exportin-2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter, CSE1L, CSE1L, CSE1L , CSE1L , CAS, CAS, CAS , CAS , XPO2, XPO2, XPO2 , XPO2 , Exportin-2, Exportin-2, Exportin-2 , Exportin-2 , Cellular apoptosis susceptibility protein, Cellular apoptosis susceptibility protein, Cellular apoptosis susceptibility protein , Cellular apoptosis susceptibility protein , Chromosome segregation 1-like protein, Chromosome segregation 1-like protein, Chromosome segregation 1-like protein , Chromosome segregation 1-like protein , Importin-alpha re-exporter, Importin-alpha re-exporter, Importin-alpha re-exporter , Importin-alpha re-exporter |
Gene, Accession # | NCBI: NP_001243064.1, NP_001307.2, UniProt: P55060 |
Catalog # | abx030969 |
Price | please inquire |
Order / More Info | Cellular Apoptosis Susceptibility Antibody from ABBEXA LTD |
Product Specific References | n/a |
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