Zona Pellucida Sperm-Binding Protein 3 (ZP3) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Zona Pellucida Sperm-Binding Protein 3 (ZP3) antibody, protein, ELISA kits.
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| Antigenic Specificity | Zona Pellucida Sperm-Binding Protein 3 (ZP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene. |
| Immunogen | KLH-conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of human ZP3. |
| Other Names | ZP3, ZP3A, ZP3B, ZPC, Zona pellucida sperm-binding protein 3, Sperm receptor, ZP3A/ZP3B, Zona pellucida glycoprotein 3, Zona pellucida protein C, Processed zona pellucida sperm-binding protein 3, ZP3, ZP3, ZP3 , ZP3 , ZP3A, ZP3A, ZP3A , ZP3A , ZP3B, ZP3B, ZP3B , ZP3B , ZPC, ZPC, ZPC , ZPC , Zona pellucida sperm-binding protein 3, Zona pellucida sperm-binding protein 3, Zona pellucida sperm-binding protein 3 , Zona pellucida sperm-binding protein 3 , Sperm receptor, Sperm receptor, Sperm receptor , Sperm receptor , ZP3A/ZP3B, ZP3A/ZP3B, ZP3A/ZP3B , ZP3A/ZP3B , Zona pellucida glycoprotein 3, Zona pellucida glycoprotein 3, Zona pellucida glycoprotein 3 , Zona pellucida glycoprotein 3 , Zona pellucida protein C, Zona pellucida protein C, Zona pellucida protein C , Zona pellucida protein C , Processed zona pellucida sperm-binding protein 3, Processed zona pellucida sperm-binding protein 3, Processed zona pellucida sperm-binding protein 3 , Processed zona pellucida sperm-binding pr |
| Gene, Accession # | ZP3, UniProt: P21754 |
| Catalog # | abx029377 |
| Price | please inquire |
| Order / More Info | Zona Pellucida Sperm-Binding Protein 3 (ZP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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