Edit |   |
---|---|
Antigenic Specificity | Glucagon (GCG) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. |
Immunogen | Purified recombinant fragment of human GCG expressed in E. Coli. |
Other Names | GCG, GLP 2, glucagon, GLP2, GLP1, GRPP Oxyntomodulin, Glicentin, Glicentin-related polypeptide, Oxyntomodulin, Glucagon-like peptide 1, Incretin hormone, Glucagon-like peptide 1 (7-37), Glucagon-like peptide 1 (7-36), Glucagon-like peptide 2, GRPP, GCG, GCG, GCG , GCG , GLP 2, GLP 2, GLP 2 , GLP 2 , glucagon, glucagon, glucagon , glucagon , GLP2, GLP2, GLP2 , GLP2 , GLP1, GLP1, GLP1 , GLP1 , GRPP Oxyntomodulin, GRPP Oxyntomodulin, GRPP Oxyntomodulin , GRPP Oxyntomodulin , Glicentin, Glicentin, Glicentin , Glicentin , Glicentin-related polypeptide, Glicentin-related polypeptide, Glicentin-related polypeptide , Glicentin-related polypeptide , Oxyntomodulin, Oxyntomodulin, Oxyntomodulin , Oxyntomodulin , Glucagon-like peptide 1, Glucagon-like peptide 1, Glucagon-like peptide 1 , Glucagon-like peptide 1 , Incretin hormone, Incretin hormone, Incretin hormone , Incretin hormone , Glucagon-like peptide 1 (7-37), Glucagon-like peptide 1 (7-37), Glucagon-like peptide 1 (7-37) , Gluc |
Gene, Accession # | GCG, Gene ID: 2641, UniProt: P01275 |
Catalog # | abx011863 |
Price | please inquire |
Order / More Info | Glucagon (GCG) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950