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Antigenic Specificity | IkB Alpha (IKBA) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from human IKB alpha (IKBA). |
Other Names | IKB alpha, IKBA, MAD3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, IKB alpha, IKB alpha, IKB alpha , IKB alpha , IKBA, IKBA, IKBA , IKBA , MAD3, MAD3, MAD3 , MAD3 , NFKBI, NFKBI, NFKBI , NFKBI , NF-kappa-B inhibitor alpha, NF-kappa-B inhibitor alpha, NF-kappa-B inhibitor alpha , NF-kappa-B inhibitor alpha , I-kappa-B-alpha, I-kappa-B-alpha, I-kappa-B-alpha , I-kappa-B-alpha , IkB-alpha, IkB-alpha, IkB-alpha , IkB-alpha , IkappaBalpha, IkappaBalpha, IkappaBalpha , IkappaBalpha , Major histocompatibility complex enhancer-binding protein MAD3, Major histocompatibility complex enhancer-binding protein MAD3, Major histocompatibility complex enhancer-binding protein MAD3 , Major histocompatibility complex enhancer-binding protein MAD3 |
Gene, Accession # | UniProt: P25963 |
Catalog # | abx031605 |
Price | please inquire |
Order / More Info | IkB Alpha (IKBA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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