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Antigenic Specificity | Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family.This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli.It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3.This kinase is phosphorylated, and thus activated by MAP3K1/MEKK.The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle.It is also widely expressed in other tissues. |
Immunogen | Purified recombinant fragment of human MAP2K4 expressed in E. coli. |
Other Names | C-Jun N-Terminal Kinase Kinase 1, Jnk-Activating Kinase 1, Mapk/Erk Kinase 4, Sapk/Erk Kinase 1, Jnkk1, Mek4, Mkk4, Prkmk4, Sek1, Serk1, Skk1, Map2K4, Dual specificity mitogen-activated protein kinase kinase 4, MEK 4, Stress-activated protein kinase kinase 1, SAP, JNKK, MAPKK4, C-Jun N-Terminal Kinase Kinase 1, C-Jun N-Terminal Kinase Kinase 1, C-Jun N-Terminal Kinase Kinase 1 , C-Jun N-Terminal Kinase Kinase 1 , Jnk-Activating Kinase 1, Jnk-Activating Kinase 1, Jnk-Activating Kinase 1 , Jnk-Activating Kinase 1 , Mapk/Erk Kinase 4, Mapk/Erk Kinase 4, Mapk/Erk Kinase 4 , Mapk/Erk Kinase 4 , Sapk/Erk Kinase 1, Sapk/Erk Kinase 1, Sapk/Erk Kinase 1 , Sapk/Erk Kinase 1 , Jnkk1, Jnkk1, Jnkk1 , Jnkk1 , Mek4, Mek4, Mek4 , Mek4 , Mkk4, Mkk4, Mkk4 , Mkk4 , Prkmk4, Prkmk4, Prkmk4 , Prkmk4 , Sek1, Sek1, Sek1 , Sek1 , Serk1, Serk1, Serk1 , Serk1 , Skk1, Skk1, Skk1 , Skk1 , Map2K4, Map2K4, Map2K4 , Map2K4 , Dual specificity mitogen-activated protein kinase kinase 4, Dual specificity mit |
Gene, Accession # | MAP2K4, Gene ID: 6416, UniProt: P45985 |
Catalog # | abx015916 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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