Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon.The transcription factor NF kappa B is retained in the cytoplasm in an inactive form by the inhibitory protein I kappa B. Activation of NF kappa B requires that I kappa B be phosphorylated on specific serine residues, which results in targeted degra-dation of I kappa B. I kappa B kinase alpha (IKK alpha), previously designated CHUK, interacts with I kappa B alpha and specifically phosphorylates I kappa B alpha on the sites that trigger its degradation, serines 32 and 36. The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma (also designated NEMO), and each appear to make essential contributions to I kappa B phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKK alpha and IKK beta. IKK-i is pri-marily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNF alpha, IL-1 and IL-6. Overexpression of IKK-i was shown to result in phosphorylation of I kappa B alpha on Ser32 and Ser36, and in NF kappa B activation, suggesting that IKK-i may act as an I kappa B kinase in the immune system. |
| Immunogen | Purified recombinant fragment of IKBKE (aa1-257) expressed in E. Coli. |
| Other Names | I kappa-B kinase epsilon, IkBKE, IKK-epsilon, IKK-E, Inducible I kappa-B kinase, IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, I kappa-B kinase epsilon, I kappa-B kinase epsilon, I kappa-B kinase epsilon , I kappa-B kinase epsilon , IkBKE, IkBKE, IkBKE , IkBKE , IKK-epsilon, IKK-epsilon, IKK-epsilon , IKK-epsilon , IKK-E, IKK-E, IKK-E , IKK-E , Inducible I kappa-B kinase, Inducible I kappa-B kinase, Inducible I kappa-B kinase , Inducible I kappa-B kinase , IKK-i, IKK-i, IKK-i , IKK-i , IKKE, IKKE, IKKE , IKKE , IKKI, IKKI, IKKI , IKKI , KIAA0151, KIAA0151, KIAA0151 , KIAA0151 , MGC125294, MGC125294, MGC125294 , MGC125294 , MGC125295, MGC125295, MGC125295 , MGC125295 , MGC125297, MGC125297, MGC125297 , MGC125297 |
| Gene, Accession # | IKBKE, Gene ID: 9641, UniProt: Q14164 |
| Catalog # | abx010992 |
| Price | please inquire |
| Order / More Info | Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies