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Antigenic Specificity | Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PLAUR Antibody is a Rabbit Polyclonal antibody against PLAUR. Urokinase plasminogen activator surface receptor (uPAR, also known as PLAUR or CD87) is a 45-65 kDa, highly glycosylated, GPI-anchored membrane protein. It contains three homologous domains (D1-D3) of which the N-terminal one (D1) represents the uPA-binding domain. After binding to uPAR, urokinase plasminogen activator (uPA) cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodelling and in many human cancers, in which it frequently indicates poor prognosis. (PMID 20027185; 12461559). |
Immunogen | Recombinant protein of human PLAUR. |
Other Names | Cd87, Plaur, D87, UPAR, URKR, MO3, Urokinase plasminogen activator surface receptor, Monocyte activation antigen Mo3, U-PAR, Cd87, Cd87, Cd87, Cd87, Plaur, Plaur, Plaur, Plaur, D87, D87, D87, D87, UPAR, UPAR, UPAR, UPAR, URKR, URKR, URKR, URKR, MO3, MO3, MO3, MO3, Urokinase plasminogen activator surface receptor, Urokinase plasminogen activator surface receptor, Urokinase plasminogen activator surface receptor, Urokinase plasminogen activator surface receptor, Monocyte activation antigen Mo3, Monocyte activation antigen Mo3, Monocyte activation antigen Mo3, Monocyte activation antigen Mo3, U-PAR, U-PAR, U-PAR, U-PAR |
Gene, Accession # | PLAUR, Gene ID: 5329, UniProt: Q03405 |
Catalog # | abx001219 |
Price | please inquire |
Order / More Info | Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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