Caspase 3 (CASP3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Caspase 3 (CASP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CASP3 antibody is a Rabbit polyclonal antibody against CASP3. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
| Immunogen | A synthetic peptide of human CASP3. |
| Other Names | CASP3, CPP32, Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p17, Caspase-3 subunit p12, CPP32B, SCA-1, CASP3, CASP3, CASP3 , CASP3 , CPP32, CPP32, CPP32 , CPP32 , Caspase-3, Caspase-3, Caspase-3 , Caspase-3 , Apopain, Apopain, Apopain , Apopain , Cysteine protease CPP32, Cysteine protease CPP32, Cysteine protease CPP32 , Cysteine protease CPP32 , Protein Yama, Protein Yama, Protein Yama , Protein Yama , SREBP cleavage activity 1, SREBP cleavage activity 1, SREBP cleavage activity 1 , SREBP cleavage activity 1 , Caspase-3 subunit p17, Caspase-3 subunit p17, Caspase-3 subunit p17 , Caspase-3 subunit p17 , Caspase-3 subunit p12, Caspase-3 subunit p12, Caspase-3 subunit p12 , Caspase-3 subunit p12 , CPP32B, CPP32B, CPP32B , CPP32B , SCA-1, SCA-1, SCA-1 , SCA-1 |
| Gene, Accession # | CASP3, Gene ID: 836, UniProt: P42574 |
| Catalog # | abx001768 |
| Price | please inquire |
| Order / More Info | Caspase 3 (CASP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950
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