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Antigenic Specificity | Dual Specificity Phosphatase 4 (DUSP4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. |
Immunogen | KLH-conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4. |
Other Names | DUSP4, MKP2, VH2, Dual specificity protein phosphatase 4, Dual specificity protein phosphatase hVH2, Mitogen-activated protein kinase phosphatase 2, MAP kinase phosphatase 2, MKP-2, TYP, HVH2, DUSP4, DUSP4, DUSP4 , DUSP4 , MKP2, MKP2, MKP2 , MKP2 , VH2, VH2, VH2 , VH2 , Dual specificity protein phosphatase 4, Dual specificity protein phosphatase 4, Dual specificity protein phosphatase 4 , Dual specificity protein phosphatase 4 , Dual specificity protein phosphatase hVH2, Dual specificity protein phosphatase hVH2, Dual specificity protein phosphatase hVH2 , Dual specificity protein phosphatase hVH2 , Mitogen-activated protein kinase phosphatase 2, Mitogen-activated protein kinase phosphatase 2, Mitogen-activated protein kinase phosphatase 2 , Mitogen-activated protein kinase phosphatase 2 , MAP kinase phosphatase 2, MAP kinase phosphatase 2, MAP kinase phosphatase 2 , MAP kinase phosphatase 2 , MKP-2, MKP-2, MKP-2 , MKP-2 , TYP, TYP, TYP , TYP , HVH2, HVH2, HVH2 , HVH2 |
Gene, Accession # | UniProt: Q13115 |
Catalog # | abx033958 |
Price | please inquire |
Order / More Info | Dual Specificity Phosphatase 4 (DUSP4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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