SRC8 Antibody from ABBEXA LTD
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|---|---|
| Antigenic Specificity | SRC8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SRC8 is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis. |
| Immunogen | KLH-conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SRC8. |
| Other Names | CTTN, EMS1, Src substrate cortactin, Amplaxin, Oncogene EMS1, CTTN, CTTN, CTTN , CTTN , EMS1, EMS1, EMS1 , EMS1 , Src substrate cortactin, Src substrate cortactin, Src substrate cortactin , Src substrate cortactin , Amplaxin, Amplaxin, Amplaxin , Amplaxin , Oncogene EMS1, Oncogene EMS1, Oncogene EMS1 , Oncogene EMS1 |
| Gene, Accession # | UniProt: Q14247 |
| Catalog # | abx034293 |
| Price | please inquire |
| Order / More Info | SRC8 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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