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Antigenic Specificity | Leucine-Rich Repeat Serine/threonine-Protein Kinase 2 (PARK8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson's disease identified to date. LRRK2, a genetic mutation, was recently found linked to about 5 percent of inherited cases of Parkinson's disease. By high-resolution recombination mapping and candidate gene sequencing in 46 families, 6 disease-segregating mutations (5 missense and 1 putative splice site mutation). It may be central to the pathogenesis of several major neurodegenerative disorders associated with parkinsonism. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains. |
Immunogen | KLH-conjugated synthetic peptide between 931-962 amino acids from human PARK8 (LRRK2). |
Other Names | LRRK2, PARK8, Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, LRRK2, LRRK2, LRRK2 , LRRK2 , PARK8, PARK8, PARK8 , PARK8 , Leucine-rich repeat serine/threonine-protein kinase 2, Leucine-rich repeat serine/threonine-protein kinase 2, Leucine-rich repeat serine/threonine-protein kinase 2 , Leucine-rich repeat serine/threonine-protein kinase 2 , Dardarin, Dardarin, Dardarin , Dardarin |
Gene, Accession # | NCBI: NP_940980.3, UniProt: Q5S007 |
Catalog # | abx033176 |
Price | please inquire |
Order / More Info | Leucine-Rich Repeat Serine/threonine-Protein Kinase 2 (PARK8) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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