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Antigenic Specificity | Signaling lymphocytic activation molecule (SLAMF1) |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Signaling lymphocytic activation molecule (SLAMF1) antibody is a Rat monoclonal antibody for the detection of CD150 (PE conjugated). CD150 is a 75-95 kDa member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembranemolecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells.The expression is upregulated upon activation. CD150 expression has been shown to bemaintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150.Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especiallywhen co-stimulated through the TCR. CD150 associates with the src homology2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to beinvolved in signal transduction. In combination with CD48, CD150 is a useful marker forhematopoieticstem cell studies. |
Immunogen | signaling lymphocytic activation molecule family member 1 |
Other Names | SLAMF1, Signaling Lymphocytic Activation Molecule Family Member 1, CD150, CD50 Antigen, Cluster of Differentiation 150, CDw150, SLAM, SLAM Family Member 1, Signaling Lymphocytic Activation Molecule, IPO-3, SLAMF1, SLAMF1, SLAMF1 , SLAMF1 , Signaling Lymphocytic Activation Molecule Family Member 1, Signaling Lymphocytic Activation Molecule Family Member 1, Signaling Lymphocytic Activation Molecule Family Member 1 , Signaling Lymphocytic Activation Molecule Family Member 1 , CD150, CD150, CD150 , CD150 , CD50 Antigen, CD50 Antigen, CD50 Antigen , CD50 Antigen , Cluster of Differentiation 150, Cluster of Differentiation 150, Cluster of Differentiation 150 , Cluster of Differentiation 150 , CDw150, CDw150, CDw150 , CDw150 , SLAM, SLAM, SLAM , SLAM , SLAM Family Member 1, SLAM Family Member 1, SLAM Family Member 1 , SLAM Family Member 1 , Signaling Lymphocytic Activation Molecule, Signaling Lymphocytic Activation Molecule, Signaling Lymphocytic Activation Molecule , Signaling Lymph |
Gene, Accession # | SLAMF1, Gene ID: 27218, UniProt: Q9QUM4 |
Catalog # | abx239873 |
Price | please inquire |
Order / More Info | Signaling lymphocytic activation molecule (SLAMF1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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