Proteasome Subunit Alpha Type 7 (PSMA7) Antibody from ABBEXA LTD
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| Antigenic Specificity | Proteasome Subunit Alpha Type 7 (PSMA7) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA7 is a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. |
| Immunogen | KLH-conjugated synthetic peptide between 100-126 amino acids from the Central region of human PSMA7. |
| Other Names | C6, HSPC, RC6-1, XAPC7, PSMA7, Proteasome subunit RC6-1 Proteasome subunit XAPC7, proteasome (prosome, macropain) subunit, alpha type, 7, MGC3755, Proteasome subunit alpha type-7, Proteasome subunit RC6-1, Proteasome subunit XAPC7, Proteasome subunit alpha 4, C6, C6, C6 , C6 , HSPC, HSPC, HSPC , HSPC , RC6-1, RC6-1, RC6-1 , RC6-1 , XAPC7, XAPC7, XAPC7 , XAPC7 , PSMA7, PSMA7, PSMA7 , PSMA7 , Proteasome subunit RC6-1 Proteasome subunit XAPC7, Proteasome subunit RC6-1 Proteasome subunit XAPC7, Proteasome subunit RC6-1 Proteasome subunit XAPC7 , Proteasome subunit RC6-1 Proteasome subunit XAPC7 , proteasome (prosome, proteasome (prosome, proteasome (prosome , proteasome (prosome , macropain) subunit, macropain) subunit, macropain) subunit , macropain) subunit , alpha type, alpha type, alpha type , alpha type , 7, 7, 7 , 7 , MGC3755, MGC3755, MGC3755 , MGC3755 , Proteasome subunit alpha type-7, Proteasome subunit alpha type-7, Proteasome subunit alpha type-7 , Proteasome subunit |
| Gene, Accession # | PSMA7, UniProt: O14818 |
| Catalog # | abx034050 |
| Price | please inquire |
| Order / More Info | Proteasome Subunit Alpha Type 7 (PSMA7) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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