Axin-2 (AXIN2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Axin-2 (AXIN2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. |
| Immunogen | KLH-conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2. |
| Other Names | AXIN2, Axin 2, Conductin, Axis Inhibition Protein 2, Axin-Like Protein, Axin-2, Axil, DKFZp781B0869, MGC126582, ODCRCS, AXIN2, AXIL, AXIN2, AXIN2, AXIN2 , AXIN2 , Axin 2, Axin 2, Axin 2 , Axin 2 , Conductin, Conductin, Conductin , Conductin , Axis Inhibition Protein 2, Axis Inhibition Protein 2, Axis Inhibition Protein 2 , Axis Inhibition Protein 2 , Axin-Like Protein, Axin-Like Protein, Axin-Like Protein , Axin-Like Protein , Axin-2, Axin-2, Axin-2 , Axin-2 , Axil, Axil, Axil , Axil , DKFZp781B0869, DKFZp781B0869, DKFZp781B0869 , DKFZp781B0869 , MGC126582, MGC126582, MGC126582 , MGC126582 , ODCRCS, ODCRCS, ODCRCS , ODCRCS , AXIN2, AXIN2, AXIN2 , AXIN2 , AXIL, AXIL, AXIL , AXIL |
| Gene, Accession # | AXIN2, Gene ID: 8313, UniProt: Q9Y2T1 |
| Catalog # | abx032512 |
| Price | please inquire |
| Order / More Info | Axin-2 (AXIN2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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