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Antigenic Specificity | Melanoma-Associated Antigen D1 (MAGED1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAGED1 antibody is a Rabbit polyclonal antibody against MAGED1. MAGE-D1, also known as NRAGE or Dlxin-1, is a member of the MAGE family of proteins. Identified as a p75 neurotrophin receptor intracellular binding protein, MAGE-D1 induces developmental apoptosis of motoneurons, and is required for p75NTR-dependent apoptosis in sympathetic neurons. It is suggested that MAGE-D1 can suppress the motility and adhesion response of tumor cells. By forming a hetercomplex with Dlx/Msx family homeodomain proteins and Necdin, MAGE-D1 modulates the function of Dlx/Msx homeodomain during terminal differentiation and maturation of neurons. MAGE-D1 is also involved in the phosphorylation of IKK-alpha/beta, and subsequent transcriptional activation of the p65 subunit of NF-kappaB, via the XIAP-Tak1-Tab1 complex. (20100315, 19639218, 17453828, 15272023) G. |
Immunogen | Recombinant protein of human MAGED1. |
Other Names | MAGED1, DLXIN-1, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, PP2250, PRO2292, MAGED1, MAGED1, MAGED1 , MAGED1 , DLXIN-1, DLXIN-1, DLXIN-1 , DLXIN-1 , NRAGE, NRAGE, NRAGE , NRAGE , Melanoma-associated antigen D1, Melanoma-associated antigen D1, Melanoma-associated antigen D1 , Melanoma-associated antigen D1 , MAGE tumor antigen CCF, MAGE tumor antigen CCF, MAGE tumor antigen CCF , MAGE tumor antigen CCF , MAGE-D1 antigen, MAGE-D1 antigen, MAGE-D1 antigen , MAGE-D1 antigen , Neurotrophin receptor-interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog , Neurotrophin receptor-interacting MAGE homolog , PP2250, PP2250, PP2250 , PP2250 , PRO2292, PRO2292, PRO2292 , PRO2292 |
Gene, Accession # | MAGED1, Gene ID: 9500, UniProt: Q9Y5V3 |
Catalog # | abx001013 |
Price | please inquire |
Order / More Info | Melanoma-Associated Antigen D1 (MAGED1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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