FAS (pY291) Antibody from ABBEXA LTD
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| Antigenic Specificity | FAS (pY291) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y291 of human FAS. |
| Other Names | Apo-1 Antigen, Apoptosis-Mediating Surface Antigen Fas, Faslg Receptor, Cd95, Apoptosis-mediating surface antigen, FAS, Apo-1, FasL receptor, TNFRSF6, TNR6, tumor necrosis factor receptor superfamily member 6, APT1, FAS1, FASTM, ALPS1A, Fas (TNF receptor superfamily, member 6), APO-1 cell surface antigen, CD95 antigen, Fas AMA, Fas antigen, OTTHUMP00000020045, OTTHUMP00000020046, OTTHUMP00000020051, OTTHUMP00000059646, apoptosis antig, Apo-1 Antigen, Apo-1 Antigen, Apo-1 Antigen , Apo-1 Antigen , Apoptosis-Mediating Surface Antigen Fas, Apoptosis-Mediating Surface Antigen Fas, Apoptosis-Mediating Surface Antigen Fas , Apoptosis-Mediating Surface Antigen Fas , Faslg Receptor, Faslg Receptor, Faslg Receptor , Faslg Receptor , Cd95, Cd95, Cd95 , Cd95 , Apoptosis-mediating surface antigen, Apoptosis-mediating surface antigen, Apoptosis-mediating surface antigen , Apoptosis-mediating surface antigen , FAS, FAS, FAS , FAS , Apo-1, Apo-1, Apo-1 , Apo-1 , FasL receptor, FasL receptor, |
| Gene, Accession # | UniProt: P25445 |
| Catalog # | abx031939 |
| Price | please inquire |
| Order / More Info | FAS (pY291) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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