FGFR1 (pY307) Antibody from ABBEXA LTD
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| Antigenic Specificity | FGFR1 (pY307) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y307 of human FGFR1. |
| Other Names | FGFR1, Fibroblast Growth Factor Receptor 1, Basic Fibroblast Growth Factor Receptor 1, Fms-Related Tyrosine Kinase 2, Proto-Oncogene C-Fgr, BFGF-R-1, FGFR-1, N-SAM, BFGFR, FGFBR, FLT-2, HBGFR, FLT2, CEK, FLG, Heparin-Binding Growth Factor Receptor, Hydroxyaryl-Protein Kinase, FMS-Like Tyrosine Kinase 2, FGFR1/PLAG1 Fusion, Pfeiffer Syndrome, CD331 Antigen, HRTFDS, CD331, ECCL, KAL2, HH2, OGD, FLT2, KAL2, BFGFR, N-SAM,Basic Fibroblast Growth Factor Receptor 1, Fms-Related Tyrosine Kinase-2, FLJ99988, OTTHUMP00000190875, OTTHUMP00000190876, OTTHUMP00000190880, basic fibroblast growth fa, MFR, H2, H3, H4, H5, C-FGR, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), FLG protein, N-sam tyrosine kinase, tyrosylprotein kinase, protein-tyrosine kinase, FMS-like tyrosine, Proto-oncogene c-Fg, FGFR1, FGFR1, FGFR1 , FGFR1 , Fibroblast Growth Factor Receptor 1, Fibroblast Growth Factor Receptor 1, Fibroblast Growth Factor Receptor 1 , Fibroblast Growth Facto |
| Gene, Accession # | UniProt: P11362 |
| Catalog # | abx031940 |
| Price | please inquire |
| Order / More Info | FGFR1 (pY307) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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