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Antigenic Specificity | Hexokinase-4 (GCK) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GCK Antibody is a Rabbit Polyclonal antibody against GCK. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
Immunogen | Recombinant protein of human GCK. |
Other Names | GCK, FGQTL3, Glucokinase, HK IV, HKIV, Hexokinase d, liver isozymes, Hexokinase-4, Hexokinase-D, HXKP, GLK, Glucokinase (hexokinase 4), Hexokinase type IV, HHF3, HK4, LGLK, MODY2, GK, GCK, GCK, GCK, GCK, FGQTL3, FGQTL3, FGQTL3, FGQTL3, Glucokinase, Glucokinase, Glucokinase, Glucokinase, HK IV, HK IV, HK IV, HK IV, HKIV, HKIV, HKIV, HKIV, Hexokinase d, Hexokinase d, Hexokinase d, Hexokinase d, liver isozymes, liver isozymes, liver isozymes, liver isozymes, Hexokinase-4, Hexokinase-4, Hexokinase-4, Hexokinase-4, Hexokinase-D, Hexokinase-D, Hexokinase-D, Hexokinase-D, HXKP, HXKP, HXKP, HXKP, GLK, GLK, GLK, GLK, Glucokinase (hexokinase 4), Glucokinase (hexokinase 4), Glucokinase (hexokinase 4), Glucokinase (hexokinase 4), Hexokinase type IV, Hexokinase type IV, Hexokinase type IV, Hexokinase type IV, HHF3, HHF3, HHF3, HHF3, HK4, HK4, HK4, HK4, LGLK, LGLK, LGLK, LGLK, MODY2, MODY2, MODY2, MODY2, GK, GK, GK, GK |
Gene, Accession # | GCK, Gene ID: 2645, UniProt: P35557 |
Catalog # | abx004809 |
Price | please inquire |
Order / More Info | Hexokinase-4 (GCK) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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