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Antigenic Specificity | MAPK/ERK Kinase Kinase 4 (MEKK4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. |
Immunogen | KLH-conjugated synthetic peptide between 235-264 amino acids from human MEKK4 (MAP2K4). |
Other Names | MAP2K4, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, Stress-activated protein kinase kinase 1, c-Jun N-terminal kinase kinase 1, MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1, Mitogen-activated protein kinase kinase kinase 4, MAP three kinase 1, MAPK/ERK kinase kinase 4, MEK kinase 4, MEKK 4, MAP2K4, MAP2K4, MAP2K4 , MAP2K4 , JNKK1, JNKK1, JNKK1 , JNKK1 , MEK4, MEK4, MEK4 , MEK4 , MKK4, MKK4, MKK4 , MKK4 , PRKMK4, PRKMK4, PRKMK4 , PRKMK4 , SEK1, SEK1, SEK1 , SEK1 , SERK1, SERK1, SERK1 , SERK1 , SKK1, SKK1, SKK1 , SKK1 , Dual specificity mitogen-activated protein kinase kinase 4, Dual specificity mitogen-activated protein kinase kinase 4, Dual specificity mitogen-activated protein kinase kinase 4 , Dual specificity mitogen-activated protein kinase kinase 4 , JNK-activating kinase 1, JNK-activating kinase 1, JNK-activating kinase 1 , JNK-activating kinase 1 , MAP |
Gene, Accession # | UniProt: P45985 |
Catalog # | abx033762 |
Price | please inquire |
Order / More Info | MAPK/ERK Kinase Kinase 4 (MEKK4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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