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Antigenic Specificity | GDNF Family Receptor Alpha 2 (GFRA2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human GFRA2. |
Other Names | GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, GFRA2, GDNFRB, RETL2, TRNR2, NTNRA, GDNF family receptor alpha-2, GDNF family receptor alpha-2, GDNF family receptor alpha-2 , GDNF family receptor alpha-2 , GDNF receptor alpha-2, GDNF receptor alpha-2, GDNF receptor alpha-2 , GDNF receptor alpha-2 , GDNFR-alpha-2, GDNFR-alpha-2, GDNFR-alpha-2 , GDNFR-alpha-2 , GFR-alpha-2, GFR-alpha-2, GFR-alpha-2 , GFR-alpha-2 , GDNF receptor beta, GDNF receptor beta, GDNF receptor beta , GDNF receptor beta , GDNFR-beta, GDNFR-beta, GDNFR-beta , GDNFR-beta , Neurturin receptor alpha, Neurturin receptor alpha, Neurturin receptor alpha , Neurturin receptor alpha , NRTNR-alpha, NRTNR-alpha, NRTNR-alpha , NRTNR-alpha , NTNR-alpha, NTNR-alpha, NTNR-alpha , NTNR-alpha , RET ligand 2, RET ligand 2, RET ligand 2 , RET ligand |
Gene, Accession # | GFRA2, UniProt: O00451 |
Catalog # | abx028008 |
Price | please inquire |
Order / More Info | GDNF Family Receptor Alpha 2 (GFRA2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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