Proteasome Activator Subunit 2 (PSME2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Proteasome Activator Subunit 2 (PSME2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PSME2 antibody is a Rabbit polyclonal antibody against PSME2. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. |
| Immunogen | Recombinant protein of human PSME2. |
| Other Names | PA28B, REGbeta, PA28beta, proteasome (prosome, macropain) activator subunit 2 (PA28 beta), PSME2, 11S regulator complex subunit beta, REG-beta Activator of multicatalytic protease subunit 2, Proteasome activator 28 subunit beta, proteasome (prosome, macropain) activator subunit 2 (PA28 beta), 11S regulator complex beta subunit, MCP activator, 31-kD subunit, activator of multicatalytic protease subunit 2, cell migration-inducing protein 22, protea, Proteasome activator complex subunit 2, PA28B, PA28B, PA28B , PA28B , REGbeta, REGbeta, REGbeta , REGbeta , PA28beta, PA28beta, PA28beta , PA28beta , proteasome (prosome, proteasome (prosome, proteasome (prosome , proteasome (prosome , macropain) activator subunit 2 (PA28 beta), macropain) activator subunit 2 (PA28 beta), macropain) activator subunit 2 (PA28 beta) , macropain) activator subunit 2 (PA28 beta) , PSME2, PSME2, PSME2 , PSME2 , 11S regulator complex subunit beta, 11S regulator complex subunit beta, 11S regulator complex sub |
| Gene, Accession # | PSME2, Gene ID: 5721, UniProt: Q9UL46 |
| Catalog # | abx004261 |
| Price | please inquire |
| Order / More Info | Proteasome Activator Subunit 2 (PSME2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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