Killer Cell Immunoglobulin Like Receptor 2DL2 (KIR2DL2) Antibody from ABBEXA LTD

Search, find, compare suppliers for anti-Killer Cell Immunoglobulin Like Receptor 2DL2 (KIR2DL2) antibody, protein, ELISA kits.

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Antigenic SpecificityKiller Cell Immunoglobulin Like Receptor 2DL2 (KIR2DL2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, FCM
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DescriptionKiller cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
ImmunogenKLH-conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human KIR2DL2.
Other NamesKIR2DL2, CD158B1, Cl-43, CD158k, MHC class I NK cell receptor, NKAT6, NKAT-6, p58 NK receptor CL-43, p58.2, CD158b, CD158b1 antigen, Killer cell immunoglobulin-like receptor 2DL2, CD158 antigen-like family member B1, Natural killer-associated transcript 6, p58 natural killer cell receptor clone CL-43, KIR2DL2, KIR2DL2, KIR2DL2 , KIR2DL2 , CD158B1, CD158B1, CD158B1 , CD158B1 , Cl-43, Cl-43, Cl-43 , Cl-43 , CD158k, CD158k, CD158k , CD158k , MHC class I NK cell receptor, MHC class I NK cell receptor, MHC class I NK cell receptor , MHC class I NK cell receptor , NKAT6, NKAT6, NKAT6 , NKAT6 , NKAT-6, NKAT-6, NKAT-6 , NKAT-6 , p58 NK receptor CL-43, p58 NK receptor CL-43, p58 NK receptor CL-43 , p58 NK receptor CL-43 , p58.2, p58.2, p58.2 , p58.2 , CD158b, CD158b, CD158b , CD158b , CD158b1 antigen, CD158b1 antigen, CD158b1 antigen , CD158b1 antigen , Killer cell immunoglobulin-like receptor 2DL2, Killer cell immunoglobulin-like receptor 2DL2, Killer cell immunoglobulin-like recep
Gene, Accession #UniProt: P43627
Catalog #abx032608
Priceplease inquire
Order / More InfoKiller Cell Immunoglobulin Like Receptor 2DL2 (KIR2DL2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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