Neprilysin / NEP (MME) Antibody from ABBEXA LTD

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Antigenic SpecificityNeprilysin / NEP (MME)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, FCM
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DescriptionMME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
ImmunogenKLH-conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin.
Other NamesMME, Membrane Metalloendopeptidase, Common Acute Lymphocytic Leukemia Antigen, Neutral Endopeptidase 24.11, Skin Fibroblast Elastase, Neutral Endopeptidase, Atriopeptidase, Enkephalinase, EC 3.4.24.11, Neprilysin, CALLA, NEP, SFE, Membrane Metallo-Endopeptidase (Neutral Endopeptidase, Enkephalinase, CALLA, CD10), Membrane Metallo-Endopeptidase Variant 1, Membrane Metallo-Endopeptidase Variant 2, Neprilysin-390, Neprilysin-411, CD10 Antigen, EC 3.4.24, CMT2T, SCA43, CD10, EPN, MME, MME, MME , MME , Membrane Metalloendopeptidase, Membrane Metalloendopeptidase, Membrane Metalloendopeptidase , Membrane Metalloendopeptidase , Common Acute Lymphocytic Leukemia Antigen, Common Acute Lymphocytic Leukemia Antigen, Common Acute Lymphocytic Leukemia Antigen , Common Acute Lymphocytic Leukemia Antigen , Neutral Endopeptidase 24.11, Neutral Endopeptidase 24.11, Neutral Endopeptidase 24.11 , Neutral Endopeptidase 24.11 , Skin Fibroblast Elastase, Skin Fibroblast Elastase, Skin Fibroblast Elasta
Gene, Accession #UniProt: P08473
Catalog #abx033331
Priceplease inquire
Order / More InfoNeprilysin / NEP (MME) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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