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Antigenic Specificity | Neprilysin / NEP (MME) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. |
Immunogen | KLH-conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin. |
Other Names | MME, Membrane Metalloendopeptidase, Common Acute Lymphocytic Leukemia Antigen, Neutral Endopeptidase 24.11, Skin Fibroblast Elastase, Neutral Endopeptidase, Atriopeptidase, Enkephalinase, EC 3.4.24.11, Neprilysin, CALLA, NEP, SFE, Membrane Metallo-Endopeptidase (Neutral Endopeptidase, Enkephalinase, CALLA, CD10), Membrane Metallo-Endopeptidase Variant 1, Membrane Metallo-Endopeptidase Variant 2, Neprilysin-390, Neprilysin-411, CD10 Antigen, EC 3.4.24, CMT2T, SCA43, CD10, EPN, MME, MME, MME , MME , Membrane Metalloendopeptidase, Membrane Metalloendopeptidase, Membrane Metalloendopeptidase , Membrane Metalloendopeptidase , Common Acute Lymphocytic Leukemia Antigen, Common Acute Lymphocytic Leukemia Antigen, Common Acute Lymphocytic Leukemia Antigen , Common Acute Lymphocytic Leukemia Antigen , Neutral Endopeptidase 24.11, Neutral Endopeptidase 24.11, Neutral Endopeptidase 24.11 , Neutral Endopeptidase 24.11 , Skin Fibroblast Elastase, Skin Fibroblast Elastase, Skin Fibroblast Elasta |
Gene, Accession # | UniProt: P08473 |
Catalog # | abx033331 |
Price | please inquire |
Order / More Info | Neprilysin / NEP (MME) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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