CD3E/CEACAM5 (Cibisatamab biosimilar) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-CD3E/CEACAM5 (Cibisatamab biosimilar) antibody, protein, ELISA kits.
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| Antigenic Specificity | CD3E/CEACAM5 (Cibisatamab biosimilar) |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 kappa/lambda with domain crossover |
| Format | Protein A/G purified |
| Size | 100 µg, 1 mg, |
| Concentration | typically between 0.5-2.0 mg/ml. |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cibisatamab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD3E/CEACAM5, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Cibisatamab (CEA-TCB) is a T cell bispecific antibody that binds carcinoembryonic antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab has a single CD3? chain binding site and two CEA binding sites on T cells (it regulates the binding affinity to cancer cells with high expression of CEA on the cell surface). This avoids targeting healthy epithelial cells with low CEA expression levels. T cell activation, cytokine secretion and release of cytotoxic particles are triggered by binding to CEA on the surface of cancer cells and CD3 on T cells. |
| Immunogen | n/a |
| Other Names | Cibisatamab, CD3E/CEACAM5, 2101242-53-7 |
| Gene, Accession # | CAS: 2101242-53-7 |
| Catalog # | abx831462 |
| Price | please inquire |
| Order / More Info | CD3E/CEACAM5 (Cibisatamab biosimilar) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
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https://www.abbexa.com
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Telephone: +44 (0) 1223 755950
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