Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody from ABBEXA LTD

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Antigenic SpecificityCircadian Locomoter Output Cycles Protein Kaput (CLOCK)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB
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DescriptionCLOCK antibody is a Rabbit polyclonal antibody against CLOCK. The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
ImmunogenA synthetic peptide of human CLOCK.
Other NamesBHLHE8, circadian locomoter output cycles kaput protein, Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, CLOCK, clock homolog (mouse), hCLOCK, KAT13D, KIAA0334, circadian locomotor output cycles kaput, BHLHE8, BHLHE8, BHLHE8 , BHLHE8 , circadian locomoter output cycles kaput protein, circadian locomoter output cycles kaput protein, circadian locomoter output cycles kaput protein , circadian locomoter output cycles kaput protein , Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles protein kaput , Circadian locomoter output cycles protein kaput , Class E basic helix-loop-helix protein 8, Class E basic helix-loop-helix protein 8, Class E basic helix-loop-helix protein 8 , Class E basic helix-loop-helix protein 8 , CLOCK, CLOCK, CLOCK , CLOCK , clock homolog (mouse), clock homolog (mouse), clock homolog (mouse) , clock homolog (mouse) , hCLOCK, hCLOCK, hCLOCK ,
Gene, Accession #CLOCK, Gene ID: 9575, UniProt: O15516
Catalog #abx004307
Priceplease inquire
Order / More InfoCircadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
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