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Antigenic Specificity | PARK8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson's disease identified to date. LRRK2, a genetic mutation, was recently found linked to about 5 percent of inherited cases of Parkinson's disease. By high-resolution recombination mapping and candidate gene sequencing in 46 families, 6 disease-segregating mutations (5 missense and 1 putative splice site mutation). It may be central to the pathogenesis of several major neurodegenerative disorders associated with parkinsonism. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains. |
Immunogen | KLH-conjugated synthetic peptide between 504-536 amino acids from human PARK8 (LRRK2). |
Other Names | LRRK2, PARK8, Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, LRRK2, LRRK2, LRRK2 , LRRK2 , PARK8, PARK8, PARK8 , PARK8 , Leucine-rich repeat serine/threonine-protein kinase 2, Leucine-rich repeat serine/threonine-protein kinase 2, Leucine-rich repeat serine/threonine-protein kinase 2 , Leucine-rich repeat serine/threonine-protein kinase 2 , Dardarin, Dardarin, Dardarin , Dardarin |
Gene, Accession # | NCBI: NP_940980.3, UniProt: Q5S007 |
Catalog # | abx033174 |
Price | please inquire |
Order / More Info | PARK8 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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