Chemokine C-X-C-Motif Receptor 4 (CXCR4) Antibody from ABBEXA LTD

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Antigenic SpecificityChemokine C-X-C-Motif Receptor 4 (CXCR4)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size100 µg,
Concentration2 mg/ml
ApplicationsELISA, WB, IHC
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DescriptionChemokine C-X-C-Motif Receptor 4 (CXCR4) antibody is a Rabbit polyclonal antibody for the detection of CXCR4.

C-X-C chemokine receptor type 4 (CXCR4) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609). CXCR4 has a calculated molecular weight of 40 kDa. In addition to the predicted species of 45-47 kDa for glycosylated CXCR4 monomers, due to ubiquitination, dimeration, and different degrees of glycosylation, additional species can also exist and have been reported in some researches, including 67 kDa (PMID: 23917520), 55, 67, 87 kDa (PMID: 20028517), 80 kDa (PMID: 10506573), 47, 50, 62, and 98 kDa (PMID: 16204649).
Immunogenchemokine (C-X-C motif) receptor 4
Other NamesCD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, Chemokine (C-X-C motif) receptor 4, CXCR4, FUSIN, CXCR4B, C-X-C chemokine receptor type 4, CCR4, CD184 antigen, CXC-R4, CXCR-4, Leukocyte-derived seven transmembrane domain receptor, SDF-1 receptor, Stromal cell- derived factor 1 receptor, CXCR4 Extracellular Loop, Cxcr4 Extracell.Loop, RABBIT A' CXCR4 EXTRACELL.LOOP, Cmkar4, Cxc chemokine receptor 4, Npyy3, C-x-c chemokine receptor 4, Neuropeptide Y receptor Y3, Stromal cell-derived factor 1 receptor, CD184, CD184, CD184 , CD184 , D2S201E, D2S201E, D2S201E , D2S201E , FB22, FB22, FB22 , FB22 , HM89, HM89, HM89 , HM89 , HSY3RR, HSY3RR, HSY3RR , HSY3RR , LAP3, LAP3, LAP3 , LAP3 , LCR1, LCR1, LCR1 , LCR1 , LESTR, LESTR, LESTR , LESTR , NPY3R, NPY3R, NPY3R , NPY3R , NPYR, NPYR, NPYR , NPYR , NPYRL, NPYRL, NPYRL , NPYRL , NPYY3R, NPYY3R, NPYY3R , NPYY3R , WHIM, WHIM, WHIM , WHIM , Chemokine (C-X-C motif) receptor 4, Chemokine (C-X-C motif
Gene, Accession #CXCR4, Gene ID: 7852, UniProt: P61073
Catalog #abx147379
Priceplease inquire
Order / More InfoChemokine C-X-C-Motif Receptor 4 (CXCR4) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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