INSR (pY1185) Antibody from ABBEXA LTD
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| Edit | |
|---|---|
| Antigenic Specificity | INSR (pY1185) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR. |
| Other Names | INSR, CD220, HHF5, Insulin receptor, Insulin receptor subunit alpha, Insulin receptor subunit beta, IR, INSR, INSR, INSR , INSR , CD220, CD220, CD220 , CD220 , HHF5, HHF5, HHF5 , HHF5 , Insulin receptor, Insulin receptor, Insulin receptor , Insulin receptor , Insulin receptor subunit alpha, Insulin receptor subunit alpha, Insulin receptor subunit alpha , Insulin receptor subunit alpha , Insulin receptor subunit beta, Insulin receptor subunit beta, Insulin receptor subunit beta , Insulin receptor subunit beta , IR, IR, IR , IR |
| Gene, Accession # | UniProt: P06213 |
| Catalog # | abx032029 |
| Price | please inquire |
| Order / More Info | INSR (pY1185) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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