Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) antibody, protein, ELISA kits.
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| Antigenic Specificity | Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. |
| Immunogen | KLH-conjugated synthetic peptide between 268-295 amino acids from the C-terminal region of human KIR2DS3. |
| Other Names | Killer cell immunoglobulin-like receptor 2DS3, MHC class I NK cell receptor, Natural killer-associated transcript 7, NKAT-7, KIR2DS3, NKAT7, Killer cell immunoglobulin-like receptor 2DS3, Killer cell immunoglobulin-like receptor 2DS3, Killer cell immunoglobulin-like receptor 2DS3 , Killer cell immunoglobulin-like receptor 2DS3 , MHC class I NK cell receptor, MHC class I NK cell receptor, MHC class I NK cell receptor , MHC class I NK cell receptor , Natural killer-associated transcript 7, Natural killer-associated transcript 7, Natural killer-associated transcript 7 , Natural killer-associated transcript 7 , NKAT-7, NKAT-7, NKAT-7 , NKAT-7 , KIR2DS3, KIR2DS3, KIR2DS3 , KIR2DS3 , NKAT7, NKAT7, NKAT7 , NKAT7 |
| Gene, Accession # | UniProt: Q14952 |
| Catalog # | abx032609 |
| Price | please inquire |
| Order / More Info | Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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