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Antigenic Specificity | Pyruvate Dehydrogenase Complex Component X (PDHX) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain. |
Immunogen | KLH-conjugated synthetic peptide between 429-459 amino acids from the C-terminal region of human PDX1. |
Other Names | GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PDHX, PDX1, Pyruvate dehydrogenase protein X component, mitochondrial, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, Lipoyl-containing pyruvate dehydrogenase complex component X, proX, Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, GSF, GSF, GSF , GSF , IPF1, IPF1, IPF1 , IPF1 , IUF1, IUF1, IUF1 , IUF1 , IDX-1, IDX-1, IDX-1 , IDX-1 , MODY4, MODY4, MODY4 , MODY4 , PDX-1, PDX-1, PDX-1 , PDX-1 , STF-1, STF-1, STF-1 , STF-1 , PDHX, PDHX, PDHX , PDHX , PDX1, PDX1, PDX1 , PDX1 , Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component , Pyruvate dehydrogenase protein X component , mitochondrial, mitochondrial, mitochondrial , mitochondrial , Dihydrolipoamide dehydrogenase-bi |
Gene, Accession # | PDHX, UniProt: O00330 |
Catalog # | abx031492 |
Price | please inquire |
Order / More Info | Pyruvate Dehydrogenase Complex Component X (PDHX) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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