Furin (FURIN) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Furin (FURIN) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Furin (FURIN) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Furin (FURIN) antibody is a Rabbit polyclonal antibody for the detection of FURIN. This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. Alternative splicing results in multiple transcript variants. |
| Immunogen | furin (paired basic amino acid cleaving enzyme) |
| Other Names | FUR, PACE, PCSK3, Furin, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, FUR, FUR, FUR , FUR , PACE, PACE, PACE , PACE , PCSK3, PCSK3, PCSK3 , PCSK3 , Furin, Furin, Furin , Furin , Dibasic-processing enzyme, Dibasic-processing enzyme, Dibasic-processing enzyme , Dibasic-processing enzyme , Paired basic amino acid residue-cleaving enzyme, Paired basic amino acid residue-cleaving enzyme, Paired basic amino acid residue-cleaving enzyme , Paired basic amino acid residue-cleaving enzyme |
| Gene, Accession # | FURIN, Gene ID: 5045, UniProt: P09958 |
| Catalog # | abx240217 |
| Price | please inquire |
| Order / More Info | Furin (FURIN) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies