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Antigenic Specificity | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) antibody is a Rabbit polyclonal antibody for the detection of DDR1. Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. |
Immunogen | discoidin domain receptor tyrosine kinase 1 |
Other Names | CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, CAK, CAK, CAK , CAK , EDDR1, EDDR1, EDDR1 , EDDR1 , NEP, NEP, NEP , NEP , NTRK4, NTRK4, NTRK4 , NTRK4 , PTK3A, PTK3A, PTK3A , PTK3A , RTK6, RTK6, RTK6 , RTK6 , TRKE, TRKE, TRKE , TRKE |
Gene, Accession # | DDR1, Gene ID: 780, UniProt: Q08345 |
Catalog # | abx146917 |
Price | please inquire |
Order / More Info | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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