Vascular Endothelial Growth Factor B (VEGFB) Antibody from ABBEXA LTD

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Antigenic SpecificityVascular Endothelial Growth Factor B (VEGFB)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionVascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFB has structural similarities to VEGF and PIGF and is frequently co-expressed with VEGF. There are two alternatively spliced isoforms of VEGFB: VEGFB 167 and VEGFB 186. VEGFB 167, a highly basic heparin-binding protein, remains with the cell or extracellular matrix whereas, VEGFB 186 is readily secreted. VEGFB stimulates endothelial cell proliferation. VEGFB binds to the tyrosine kinase receptor VEGFR1 (flt1) and does not bind to VEGFR2. Vascular Endothelial Growth Factor B is widely expressed but is most abundant in heart, skeletal muscle, and pancreas. It has been suggested that VEGFB expression in human primary breast cancers is associated with lymph node metastasis. The genes that encode VEGFB have been mapped to chromosome 11q13.
ImmunogenKLH-conjugated synthetic peptide between 110-139 amino acids from the Central region of human VEGFB (VEGF2).
Other NamesVascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VEGFL, Vascular endothelial growth factor B, Vascular endothelial growth factor B, Vascular endothelial growth factor B , Vascular endothelial growth factor B , VEGF-B, VEGF-B, VEGF-B , VEGF-B , VEGF-related factor, VEGF-related factor, VEGF-related factor , VEGF-related factor , VRF, VRF, VRF , VRF , VEGFB, VEGFB, VEGFB , VEGFB , VEGFL, VEGFL, VEGFL , VEGFL
Gene, Accession #UniProt: P49765
Catalog #abx025109
Priceplease inquire
Order / More InfoVascular Endothelial Growth Factor B (VEGFB) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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