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Antigenic Specificity | Mitogen-Activated Protein Kinase 15 (MAPK15) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions. |
Immunogen | KLH-conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15. |
Other Names | Extracellular signal-regulated kinase 8, MAP kinase 15, MAPK 15, Extracellular signal-regulated kinase 7, ERK-7, ERK-8, MAPK15, ERK7, ERK8, Mitogen-activated protein kinase 15, Extracellular signal-regulated kinase 8, Extracellular signal-regulated kinase 8, Extracellular signal-regulated kinase 8 , Extracellular signal-regulated kinase 8 , MAP kinase 15, MAP kinase 15, MAP kinase 15 , MAP kinase 15 , MAPK 15, MAPK 15, MAPK 15 , MAPK 15 , Extracellular signal-regulated kinase 7, Extracellular signal-regulated kinase 7, Extracellular signal-regulated kinase 7 , Extracellular signal-regulated kinase 7 , ERK-7, ERK-7, ERK-7 , ERK-7 , ERK-8, ERK-8, ERK-8 , ERK-8 , MAPK15, MAPK15, MAPK15 , MAPK15 , ERK7, ERK7, ERK7 , ERK7 , ERK8, ERK8, ERK8 , ERK8 , Mitogen-activated protein kinase 15, Mitogen-activated protein kinase 15, Mitogen-activated protein kinase 15 , Mitogen-activated protein kinase 15 |
Gene, Accession # | UniProt: Q8TD08 |
Catalog # | abx033471 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase 15 (MAPK15) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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