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Antigenic Specificity | Mouse Il12b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity). Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Immunogen | KLH-conjugated synthetic peptide between 196-222 amino acids from the Central region of mouse Il12b. |
Other Names | Il12b, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, Il12b, Il12b, Il12b , Il12b , Interleukin-12 subunit beta, Interleukin-12 subunit beta, Interleukin-12 subunit beta , Interleukin-12 subunit beta , Cytotoxic lymphocyte maturation factor 40 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit , Cytotoxic lymphocyte maturation factor 40 kDa subunit , IL-12 subunit p40, IL-12 subunit p40, IL-12 subunit p40 , IL-12 subunit p40 |
Gene, Accession # | UniProt: P43432 |
Catalog # | abx030496 |
Price | please inquire |
Order / More Info | Mouse Il12b Antibody from ABBEXA LTD |
Product Specific References | n/a |
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