Mouse Il12b Antibody from ABBEXA LTD

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Antigenic SpecificityMouse Il12b
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity). Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
ImmunogenKLH-conjugated synthetic peptide between 196-222 amino acids from the Central region of mouse Il12b.
Other NamesIl12b, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, Il12b, Il12b, Il12b , Il12b , Interleukin-12 subunit beta, Interleukin-12 subunit beta, Interleukin-12 subunit beta , Interleukin-12 subunit beta , Cytotoxic lymphocyte maturation factor 40 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit , Cytotoxic lymphocyte maturation factor 40 kDa subunit , IL-12 subunit p40, IL-12 subunit p40, IL-12 subunit p40 , IL-12 subunit p40
Gene, Accession #UniProt: P43432
Catalog #abx030496
Priceplease inquire
Order / More InfoMouse Il12b Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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