IL6R/CD126 (Sarilumab biosimilar) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-IL6R/CD126 (Sarilumab biosimilar) antibody, protein, ELISA kits.
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| Antigenic Specificity | IL6R/CD126 (Sarilumab biosimilar) |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein A/G purified |
| Size | 100 µg, 1 mg, |
| Concentration | typically between 0.5-2.0 mg/ml. |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Sarilumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL6R/CD126, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Sarilumab is a fully human anti-IL-6R monoclonal IgG1 antibody that binds to both membrane bound and soluble interleukin 6 (IL-6) receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6 1. Sarilumab was developped by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe Rheumatoid Arthritis (RA) in combination with methotrexate 4. RA is a chronic inflammatory disease characterized by polyarthritis and its treatment has been challenged by the different response in every patient 3. Subcutaneous administration of Sarilumab has been shown to decrease acute-phase reactant levels and improve in clinical RA symptoms 2. |
| Immunogen | n/a |
| Other Names | Sarilumab, IL6R/CD126, 1189541-98-7 |
| Gene, Accession # | CAS: 1189541-98-7 |
| Catalog # | abx831234 |
| Price | please inquire |
| Order / More Info | IL6R/CD126 (Sarilumab biosimilar) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
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Telephone: +44 (0) 1223 755950
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