Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) Antibody from ABBEXA LTD
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| Antigenic Specificity | Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. |
| Immunogen | KLH-conjugated synthetic peptide between 117-146 amino acids from the C-terminal region of human CDKN1A. |
| Other Names | CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, CDKN1A, MDA6, PIC1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, CAP20, CAP20, CAP20 , CAP20 , CDKN1, CDKN1, CDKN1 , CDKN1 , CIP1, CIP1, CIP1 , CIP1 , MDA-6, MDA-6, MDA-6 , MDA-6 , P21, P21, P21 , P21 , SDI1, SDI1, SDI1 , SDI1 , WAF1, WAF1, WAF1 , WAF1 , p21CIP1, p21CIP1, p21CIP1 , p21CIP1 , CDKN1A, CDKN1A, CDKN1A , CDKN1A , MDA6, MDA6, MDA6 , MDA6 , PIC1, PIC1, PIC1 , PIC1 , Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1 , Cyclin-dependent kinase inhibitor 1 , CDK-interacting protein 1, CDK-interacting protein 1, CDK-interacting protein 1 , CDK-interacting protein 1 , Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein 6 , Melanoma differentiation-associated protein 6 |
| Gene, Accession # | UniProt: P38936 |
| Catalog # | abx027406 |
| Price | please inquire |
| Order / More Info | Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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