TNFSF11/CD254 (Denosumab biosimilar) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-TNFSF11/CD254 (Denosumab biosimilar) antibody, protein, ELISA kits.
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| Antigenic Specificity | TNFSF11/CD254 (Denosumab biosimilar) |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG2 kappa |
| Format | Protein A/G purified |
| Size | 100 µg, 1 mg, |
| Concentration | typically between 0.5-2.0 mg/ml. |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Denosumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting TNFSF11/CD254, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010. |
| Immunogen | n/a |
| Other Names | Denosumab, TNFSF11/CD254, 615258-40-7 |
| Gene, Accession # | CAS: 615258-40-7 |
| Catalog # | abx831133 |
| Price | please inquire |
| Order / More Info | TNFSF11/CD254 (Denosumab biosimilar) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950
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