WNT1 Inducible Signaling Pathway Protein 1 / WISP1 (CCN4) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-WNT1 Inducible Signaling Pathway Protein 1 / WISP1 (CCN4) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | WNT1 Inducible Signaling Pathway Protein 1 / WISP1 (CCN4) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | WISP1 Antibody is a Rabbit Polyclonal antibody against WISP1. This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified. |
| Immunogen | Recombinant protein of human WISP1. |
| Other Names | WISP1, WNT1 inducible signaling pathway protein 1, CCN4, WISP1c, WISP1i, WISP1tc, WNT1 induced secreted protein 1, Wnt-1 inducible signaling pathway protein 1, wnt-1 signaling pathway protein 1, WISP1, WISP1, WISP1, WISP1, WNT1 inducible signaling pathway protein 1, WNT1 inducible signaling pathway protein 1, WNT1 inducible signaling pathway protein 1, WNT1 inducible signaling pathway protein 1, CCN4, CCN4, CCN4, CCN4, WISP1c, WISP1c, WISP1c, WISP1c, WISP1i, WISP1i, WISP1i, WISP1i, WISP1tc, WISP1tc, WISP1tc, WISP1tc, WNT1 induced secreted protein 1, WNT1 induced secreted protein 1, WNT1 induced secreted protein 1, WNT1 induced secreted protein 1, Wnt-1 inducible signaling pathway protein 1, Wnt-1 inducible signaling pathway protein 1, Wnt-1 inducible signaling pathway protein 1, Wnt-1 inducible signaling pathway protein 1, wnt-1 signaling pathway protein 1, wnt-1 signaling pathway protein 1, wnt-1 signaling pathway protein 1, wnt-1 signaling pathway protein 1 |
| Gene, Accession # | WISP1, Gene ID: 8840, UniProt: O95388 |
| Catalog # | abx002388 |
| Price | please inquire |
| Order / More Info | WNT1 Inducible Signaling Pathway Protein 1 / WISP1 (CCN4) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies