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Antigenic Specificity | Suppressor of Variegation 3-9 Homolog 2 (SUV39H2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis. |
Immunogen | KLH-conjugated synthetic peptide between 367-395 amino acids from the C-terminal region of human SUV39H2. |
Other Names | FLJ23414, KMT1B, Histone H3-K9 methyltransferase 2, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2, SUV39H2, Histone-lysine N-methyltransferase SUV39H2, Su (var)3-9 homolog 2, suppressor of variegation 3-9 homolog 2 (Drosophila), suppressor of variation 3-9 (Drosophila) homolog 2 (Drosophila), RP11-2K17.2, KMT1, uppressor of variegation 3-9 homolog 2 (Drosophila), FLJ23414, FLJ23414, FLJ23414 , FLJ23414 , KMT1B, KMT1B, KMT1B , KMT1B , Histone H3-K9 methyltransferase 2, Histone H3-K9 methyltransferase 2, Histone H3-K9 methyltransferase 2 , Histone H3-K9 methyltransferase 2 , H3-K9-HMTase 2, H3-K9-HMTase 2, H3-K9-HMTase 2 , H3-K9-HMTase 2 , Lysine N-methyltransferase 1B, Lysine N-methyltransferase 1B, Lysine N-methyltransferase 1B , Lysine N-methyltransferase 1B , Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3-9 homolog 2 , Suppressor of variegation 3-9 homol |
Gene, Accession # | SUV39H2, UniProt: Q9H5I1 |
Catalog # | abx030784 |
Price | please inquire |
Order / More Info | Suppressor of Variegation 3-9 Homolog 2 (SUV39H2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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