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Antigenic Specificity | Rho-Related GTP-Binding Protein RhoE (ARHE) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925) ; GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855) ; and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]). |
Immunogen | KLH-conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE. |
Other Names | RND3, ARHE, RHO8, RHOE, Rho-related GTP-binding protein RhoE, Protein MemB, Rho family GTPase 3, Rho-related GTP-binding protein Rho8, RND3, RND3, RND3 , RND3 , ARHE, ARHE, ARHE , ARHE , RHO8, RHO8, RHO8 , RHO8 , RHOE, RHOE, RHOE , RHOE , Rho-related GTP-binding protein RhoE, Rho-related GTP-binding protein RhoE, Rho-related GTP-binding protein RhoE , Rho-related GTP-binding protein RhoE , Protein MemB, Protein MemB, Protein MemB , Protein MemB , Rho family GTPase 3, Rho family GTPase 3, Rho family GTPase 3 , Rho family GTPase 3 , Rho-related GTP-binding protein Rho8, Rho-related GTP-binding protein Rho8, Rho-related GTP-binding protein Rho8 , Rho-related GTP-binding protein Rho8 |
Gene, Accession # | UniProt: P61587 |
Catalog # | abx033659 |
Price | please inquire |
Order / More Info | Rho-Related GTP-Binding Protein RhoE (ARHE) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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