Edit |   |
---|---|
Antigenic Specificity | Actinin Alpha 2 (ACTN2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACTN2 antibody is a Rabbit polyclonal antibody against ACTN2. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant protein of human ACTN2. |
Other Names | ACTN2, Actinin, alpha 2, Alpha-actinin skeletal muscle, CMD1AA, F-actin cross-linking protein, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, ACTN2, ACTN2, ACTN2 , ACTN2 , Actinin, Actinin, Actinin , Actinin , alpha 2, alpha 2, alpha 2 , alpha 2 , Alpha-actinin skeletal muscle, Alpha-actinin skeletal muscle, Alpha-actinin skeletal muscle , Alpha-actinin skeletal muscle , CMD1AA, CMD1AA, CMD1AA , CMD1AA , F-actin cross-linking protein, F-actin cross-linking protein, F-actin cross-linking protein , F-actin cross-linking protein , Alpha-actinin-2, Alpha-actinin-2, Alpha-actinin-2 , Alpha-actinin-2 , Alpha-actinin skeletal muscle isoform 2, Alpha-actinin skeletal muscle isoform 2, Alpha-actinin skeletal muscle isoform 2 , Alpha-actinin skeletal muscle isoform 2 |
Gene, Accession # | ACTN2, Gene ID: 88, UniProt: P35609 |
Catalog # | abx002676 |
Price | please inquire |
Order / More Info | Actinin Alpha 2 (ACTN2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950