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Antigenic Specificity | Surfactant Protein B (SFTPB) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SFTPB is the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified. |
Immunogen | KLH-conjugated synthetic peptide between 129-158 amino acids from the Central region of human SFTPB. |
Other Names | SFTPB, SFTP3, Pulmonary surfactant-associated protein B, 18 kDa pulmonary-surfactant protein, 6 kDa protein, Pulmonary surfactant-associated proteolipid SPL (Phe), SFTPB, SFTPB, SFTPB , SFTPB , SFTP3, SFTP3, SFTP3 , SFTP3 , Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated protein B , Pulmonary surfactant-associated protein B , 18 kDa pulmonary-surfactant protein, 18 kDa pulmonary-surfactant protein, 18 kDa pulmonary-surfactant protein , 18 kDa pulmonary-surfactant protein , 6 kDa protein, 6 kDa protein, 6 kDa protein , 6 kDa protein , Pulmonary surfactant-associated proteolipid SPL (Phe), Pulmonary surfactant-associated proteolipid SPL (Phe), Pulmonary surfactant-associated proteolipid SPL (Phe) , Pulmonary surfactant-associated proteolipid SPL (Phe) |
Gene, Accession # | UniProt: P07988 |
Catalog # | abx028735 |
Price | please inquire |
Order / More Info | Surfactant Protein B (SFTPB) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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