MCK10 Antibody from ABBEXA LTD
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| Antigenic Specificity | MCK10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. |
| Immunogen | Recombinant human MCK10 protein. |
| Other Names | DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD167a, DDR1, DDR1, DDR1 , DDR1 , CAK, CAK, CAK , CAK , EDDR1, EDDR1, EDDR1 , EDDR1 , NEP, NEP, NEP , NEP , NTRK4, NTRK4, NTRK4 , NTRK4 , PTK3A, PTK3A, PTK3A , PTK3A , RTK6, RTK6, RTK6 , RTK6 , TRKE, TRKE, TRKE , TRKE , Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain-containing receptor 1 , Epithelial discoidin domain-containing receptor 1 , CD167 antigen-like family member A, CD167 antigen-like family member A, CD167 antigen-like family member A , CD167 antigen-like family member A , Cell adhesion kinase, Cell adhesion kinase, Cell adhesion kinase , Cell |
| Gene, Accession # | UniProt: Q08345 |
| Catalog # | abx033584 |
| Price | please inquire |
| Order / More Info | MCK10 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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