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Antigenic Specificity | 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PSMD4 antibody is a Rabbit polyclonal against PSMD4. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. |
Immunogen | proteasome(prosome, macropain) 26S subunit, non-ATPase, 4 |
Other Names | MCB1, 26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, Antisecretory factor 1, AF, ASF, Multiubiquitin chain-binding protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, PSMD4, AF-1, Rpn10, S5A, pUB-R5, MCB1, MCB1, MCB1 , MCB1 , 26S proteasome non-ATPase regulatory subunit 4, 26S proteasome non-ATPase regulatory subunit 4, 26S proteasome non-ATPase regulatory subunit 4 , 26S proteasome non-ATPase regulatory subunit 4 , 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit RPN10 , 26S proteasome regulatory subunit RPN10 , 26S proteasome regulatory subunit S5A, 26S proteasome regulatory subunit S5A, 26S proteasome regulatory subunit S5A , 26S proteasome regulatory subunit S5A , Antisecretory factor 1, Antisecretory factor 1, Antisecretory factor 1 , Antisecretory factor 1 , AF, AF, AF , AF , ASF, ASF, ASF , ASF , Multiubiquiti |
Gene, Accession # | PSMD4, Gene ID: 5710, NCBI: NP_002801.1, NM_002810.2, UniProt: P55036 |
Catalog # | abx236889 |
Price | please inquire |
Order / More Info | 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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