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Antigenic Specificity | MAPK/ERK Kinase Kinase 1 (MEKK1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases. It is also a highly efficient activator of the JNK cascade. The protein contains a putative 1 RING-type zinc finger and 1 SWIM-type zinc finger. |
Immunogen | KLH-conjugated synthetic peptide between 1145-1176 amino acids from the C-terminal region of human MEKK1. |
Other Names | MAP3K1, MAPKKK1, MEKK, MEKK1, Mitogen-activated protein kinase kinase kinase 1, MAPK/ERK kinase kinase 1, MEK kinase 1, MEKK 1, MAP3K1, MAP3K1, MAP3K1 , MAP3K1 , MAPKKK1, MAPKKK1, MAPKKK1 , MAPKKK1 , MEKK, MEKK, MEKK , MEKK , MEKK1, MEKK1, MEKK1 , MEKK1 , Mitogen-activated protein kinase kinase kinase 1, Mitogen-activated protein kinase kinase kinase 1, Mitogen-activated protein kinase kinase kinase 1 , Mitogen-activated protein kinase kinase kinase 1 , MAPK/ERK kinase kinase 1, MAPK/ERK kinase kinase 1, MAPK/ERK kinase kinase 1 , MAPK/ERK kinase kinase 1 , MEK kinase 1, MEK kinase 1, MEK kinase 1 , MEK kinase 1 , MEKK 1, MEKK 1, MEKK 1 , MEKK 1 |
Gene, Accession # | UniProt: Q13233 |
Catalog # | abx033756 |
Price | please inquire |
Order / More Info | MAPK/ERK Kinase Kinase 1 (MEKK1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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