Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) Antibody from ABBEXA LTD

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Antigenic SpecificityEgl-9 Family Hypoxia Inducible Factor 3 (EGLN3)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionEGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism (By similarity).
ImmunogenKLH-conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human EGLN3.
Other NamesEGLN3, egl nine homolog 3 (C. elegans), FLJ21620, HIFPH3, MGC125998, MGC125999, PHD3, EGL nine (C.elegans) homolog 3, egl nine homolog 3, egl nine-like protein 3 isoform, HPH-1, Hypoxia-inducible factor prolyl hydroxylase 3, Prolyl hydroxylase domain-containing protein 3, HIF-PH3, HIF-prolyl hydroxylase 3, HPH-3, SM-20, HIFP4H3, EGLN3, EGLN3, EGLN3 , EGLN3 , egl nine homolog 3 (C. elegans), egl nine homolog 3 (C. elegans), egl nine homolog 3 (C. elegans) , egl nine homolog 3 (C. elegans) , FLJ21620, FLJ21620, FLJ21620 , FLJ21620 , HIFPH3, HIFPH3, HIFPH3 , HIFPH3 , MGC125998, MGC125998, MGC125998 , MGC125998 , MGC125999, MGC125999, MGC125999 , MGC125999 , PHD3, PHD3, PHD3 , PHD3 , EGL nine (C.elegans) homolog 3, EGL nine (C.elegans) homolog 3, EGL nine (C.elegans) homolog 3 , EGL nine (C.elegans) homolog 3 , egl nine homolog 3, egl nine homolog 3, egl nine homolog 3 , egl nine homolog 3 , egl nine-like protein 3 isoform, egl nine-like protein 3 isoform, egl nine-like protein 3
Gene, Accession #EGLN3, UniProt: Q9H6Z9
Catalog #abx027889
Priceplease inquire
Order / More InfoEgl-9 Family Hypoxia Inducible Factor 3 (EGLN3) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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