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Antigenic Specificity | Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human EGLN3. |
Other Names | EGLN3, egl nine homolog 3 (C. elegans), FLJ21620, HIFPH3, MGC125998, MGC125999, PHD3, EGL nine (C.elegans) homolog 3, egl nine homolog 3, egl nine-like protein 3 isoform, HPH-1, Hypoxia-inducible factor prolyl hydroxylase 3, Prolyl hydroxylase domain-containing protein 3, HIF-PH3, HIF-prolyl hydroxylase 3, HPH-3, SM-20, HIFP4H3, EGLN3, EGLN3, EGLN3 , EGLN3 , egl nine homolog 3 (C. elegans), egl nine homolog 3 (C. elegans), egl nine homolog 3 (C. elegans) , egl nine homolog 3 (C. elegans) , FLJ21620, FLJ21620, FLJ21620 , FLJ21620 , HIFPH3, HIFPH3, HIFPH3 , HIFPH3 , MGC125998, MGC125998, MGC125998 , MGC125998 , MGC125999, MGC125999, MGC125999 , MGC125999 , PHD3, PHD3, PHD3 , PHD3 , EGL nine (C.elegans) homolog 3, EGL nine (C.elegans) homolog 3, EGL nine (C.elegans) homolog 3 , EGL nine (C.elegans) homolog 3 , egl nine homolog 3, egl nine homolog 3, egl nine homolog 3 , egl nine homolog 3 , egl nine-like protein 3 isoform, egl nine-like protein 3 isoform, egl nine-like protein 3 |
Gene, Accession # | EGLN3, UniProt: Q9H6Z9 |
Catalog # | abx027889 |
Price | please inquire |
Order / More Info | Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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