DNA Fragmentation Factor Subunit Beta (DFFB) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-DNA Fragmentation Factor Subunit Beta (DFFB) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DNA Fragmentation Factor Subunit Beta (DFFB) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DFFB. |
| Other Names | DFFB, CAD, DFF2, DFF40, DNA fragmentation factor subunit beta, Caspase-activated deoxyribonuclease, Caspase-activated nuclease, DNA fragmentation factor 40 kDa subunit, dffb-, DFFB, DFFB, DFFB , DFFB , CAD, CAD, CAD , CAD , DFF2, DFF2, DFF2 , DFF2 , DFF40, DFF40, DFF40 , DFF40 , DNA fragmentation factor subunit beta, DNA fragmentation factor subunit beta, DNA fragmentation factor subunit beta , DNA fragmentation factor subunit beta , Caspase-activated deoxyribonuclease, Caspase-activated deoxyribonuclease, Caspase-activated deoxyribonuclease , Caspase-activated deoxyribonuclease , Caspase-activated nuclease, Caspase-activated nuclease, Caspase-activated nuclease , Caspase-activated nuclease , DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor 40 kDa subunit , DNA fragmentation factor 40 kDa subunit , dffb-, dffb-, dffb- , dffb- |
| Gene, Accession # | DFFB, UniProt: O76075 |
| Catalog # | abx034537 |
| Price | please inquire |
| Order / More Info | DNA Fragmentation Factor Subunit Beta (DFFB) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies