E3 Ubiquitin-Protein Ligase XIAP (XIAP) Antibody from ABBEXA LTD

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Antigenic SpecificityE3 Ubiquitin-Protein Ligase XIAP (XIAP)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC
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DescriptionXIAP antibody is a Rabbit polyclonal antibody against XIAP. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
ImmunogenRecombinant protein of human XIAP.
Other NamesBaculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, Baculoviral IAP repeat-containing protein 4, Baculoviral IAP repeat-containing protein 4 , Baculoviral IAP repeat-containing protein 4 , IAP-like protein, IAP-like protein, IAP-like protein , IAP-like protein , ILP, ILP, ILP , ILP , hILP, hILP, hILP , hILP , Inhibitor of apoptosis protein 3, Inhibitor of apoptosis protein 3, Inhibitor of apoptosis protein 3 , Inhibitor of apoptosis protein 3 , IAP-3, IAP-3, IAP-3 , IAP-3 , hIAP-3, hIAP-3, hIAP-3 , hIAP-3 , hIAP3, hIAP3, hIAP3 , hIAP3 , X-linked inhibitor of apoptosis protein, X-linked inhibitor of apoptosis protein, X-linked inhibitor of apoptosis protein , X-linked inhibitor of apoptosis protein , X-linked IAP, X-linked IAP, X-linked IAP , X
Gene, Accession #XIAP, Gene ID: 331, UniProt: P98170
Catalog #abx005234
Priceplease inquire
Order / More InfoE3 Ubiquitin-Protein Ligase XIAP (XIAP) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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