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Antigenic Specificity | E3 Ubiquitin-Protein Ligase XIAP (XIAP) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | XIAP antibody is a Rabbit polyclonal antibody against XIAP. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11. |
Immunogen | Recombinant protein of human XIAP. |
Other Names | Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, Baculoviral IAP repeat-containing protein 4, Baculoviral IAP repeat-containing protein 4 , Baculoviral IAP repeat-containing protein 4 , IAP-like protein, IAP-like protein, IAP-like protein , IAP-like protein , ILP, ILP, ILP , ILP , hILP, hILP, hILP , hILP , Inhibitor of apoptosis protein 3, Inhibitor of apoptosis protein 3, Inhibitor of apoptosis protein 3 , Inhibitor of apoptosis protein 3 , IAP-3, IAP-3, IAP-3 , IAP-3 , hIAP-3, hIAP-3, hIAP-3 , hIAP-3 , hIAP3, hIAP3, hIAP3 , hIAP3 , X-linked inhibitor of apoptosis protein, X-linked inhibitor of apoptosis protein, X-linked inhibitor of apoptosis protein , X-linked inhibitor of apoptosis protein , X-linked IAP, X-linked IAP, X-linked IAP , X |
Gene, Accession # | XIAP, Gene ID: 331, UniProt: P98170 |
Catalog # | abx005234 |
Price | please inquire |
Order / More Info | E3 Ubiquitin-Protein Ligase XIAP (XIAP) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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