FGF Receptor 1 (pY653) Antibody from ABBEXA LTD
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| Antigenic Specificity | FGF Receptor 1 (pY653) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FGF Receptor 1 (pY653) Antibody is a Rabbit Polyclonal antibody against FGF Receptor 1 (pY653). The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y653 of human FGF Receptor 1. |
| Other Names | FGFR1, CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, FLT-2, HBGFR, N-SAM, FGFR-1, bFGF-R-1, FLJ99988, FGFR1, FGFR1, FGFR1, FGFR1, CEK, CEK, CEK, CEK, FLG, FLG, FLG, FLG, OGD, OGD, OGD, OGD, FLT2, FLT2, FLT2, FLT2, KAL2, KAL2, KAL2, KAL2, BFGFR, BFGFR, BFGFR, BFGFR, CD331, CD331, CD331, CD331, FGFBR, FGFBR, FGFBR, FGFBR, FLT-2, FLT-2, FLT-2, FLT-2, HBGFR, HBGFR, HBGFR, HBGFR, N-SAM, N-SAM, N-SAM, N-SAM, FGFR-1, FGFR-1, FGFR-1, FGFR-1, bFGF-R-1, bFGF-R-1, bFGF-R-1, bFGF-R-1, FLJ99988, FLJ99988, FLJ99988, FLJ99988 |
| Gene, Accession # | FGFR1, Gene ID: 2260, UniProt: P11362 |
| Catalog # | abx000121 |
| Price | please inquire |
| Order / More Info | FGF Receptor 1 (pY653) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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